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一.MONSANTO販賣哪些GMO種子?
A: Corn(玉米),Cotton(棉花),Oilseeds(油菜子),Watermelon(西瓜),Carrot(胡蘿蔔)
二.ROCHE藥品所治療的疾病包含哪些?
A: Tamitlu - 克流感 - 流行性感冒
Xenical - 羅氏鮮 - 減肥
Herceptin - 賀癌平 - 治癌症
三.PFIZER除威爾剛之外,還有什麼藥?
A: Caverject , Glucotrol , Sinequan
四.Perkin Elmer賣什麼儀器?
A: Lab Automation , Medical Lighting , Raman Spectroscopy
五.ABI需要什麼人才?
A: Sales , Marketing , Purchasing
基因名稱:leptin
基因編碼:NM_005073
基因大小:3104 bp
生物體:Homo sapiens (human)
DNA序列:
1 cacctgccag gagcacgtcc cgccggcagt cgcaggagcc ctgggagccg ccgccatggg
61 aatgtccaaa tcacacagtt tctttggtta tcccctgagc atcttcttca tcgtggtcaa
121 tgagttttgc gaaagatttt cctactatgg aatgcgagca atcctgattc tgtacttcac
181 aaatttcatc agctgggatg ataacctgtc caccgccatc taccatacgt ttgtggctct
241 gtgctacctg acgccaattc tcggagctct tatcgccgac tcgtggctgg gaaagttcaa
301 gaccattgtg tcgctctcca ttgtctacac aattggacaa gcagtcacct cagtaagctc
361 cattaatgac ctcacagacc acaaccatga tggcaccccc gacagccttc ctgtgcacgt
421 ggtgctgtcc ttgatcggcc tggccctgat agctctcggg actggaggaa tcaaaccctg
481 tgtgtctgcg tttggtggag atcagtttga agagggccag gagaaacaaa gaaacagatt
541 tttttccatc ttttacttgg ctattaatgc tggaagtttg ctttccacaa tcatcacacc
601 catgctcaga gttcaacaat gtggaattca cagtaaacaa gcttgttacc cactggcctt
661 tggggttcct gctgctctca tggctgtagc cctgattgtg tttgtccttg gcagtgggat
721 gtacaagaag ttcaagccac agggcaacat catgggtaaa gtggccaagt gcatcggttt
781 tgccatcaaa aatagattta ggcatcggag taaggcattt cccaagaggg agcactggct
841 ggactgggct aaagagaaat acgatgagcg gctcatctcc caaattaaga tggttacgag
901 ggtgatgttc ctgtatattc cactcccaat gttctgggcc ttgtttgacc agcagggctc
961 caggtggaca ctgcaggcaa caactatgtc cgggaaaatc ggagctcttg aaattcagcc
1021 cgatcagatg cagaccgtga acgccatcct gatcgtgatc atggtcccga tcttcgatgc
1081 tgtgctgtac cctctcattg caaaatgtgg cttcaatttc acctccttga agaagatggc
1141 agttggcatg gtcctggcct ccatggcctt tgtggtggct gccatcgtgc aggtggaaat
1201 cgataaaact cttccagtct tccccaaagg aaacgaagtc caaattaaag ttttgaatat
1261 aggaaacaat accatgaata tatctcttcc tggagagatg gtgacacttg gcccaatgtc
1321 tcaaacaaat gcatttatga cttttgatgt aaacaaactg acaaggataa acatttcttc
1381 tcctggatca ccagtcactg ctgtaactga cgacttcaag cagggccaac gccacacgct
1441 tctagtgtgg gcccccaatc actaccaggt ggtaaaggat ggtcttaacc agaagccaga
1501 aaaaggggaa aatggaatca gatttgtaaa tacttttaac gagctcatca ccatcacaat
1561 gagtgggaaa gtttatgcaa acatcagcag ctacaatgcc agcacatacc agttttttcc
1621 ttctggcata aaaggcttca caataagctc aacagagatt ccgccacaat gtcaacctaa
1681 tttcaatact ttctaccttg aatttggtag tgcttatacc tatatagtcc aaaggaagaa
1741 tgacagctgc cctgaagtga aggtgtttga agatatttca gccaacacag ttaacatggc
1801 tctgcaaatc ccgcagtatt ttcttctcac ctgtggcgaa gtggtcttct ctgtcacggg
1861 attggaattc tcatattctc aggctccttc caacatgaag tcggtgcttc aggcaggatg
1921 gctgctgacc gtggctgttg gcaacatcat tgtgctcatc gtggcagggg caggccagtt
1981 cagcaaacag tgggccgagt acattctatt tgccgcgttg cttctggtcg tctgtgtaat
2041 ttttgccatc atggctcggt tctatactta catcaaccca gcggagatcg aagctcaatt
2101 tgatgaggat gaaaagaaaa acagactgga aaagagtaac ccatatttca tgtcaggggc
2161 caattcacag aaacagatgt gaaggtcagg aggcaagtgg aggatggact gggcccgcag
2221 atgccctgac ctctgccccc aggtagcagg acactccatt ggatggcccc tgatgaggaa
2281 gacttcagaa ttgggaacta aaccatgaat gctattttct tttttctttt tcttttcttt
2341 tttttttttt tttttttgag acagagtttt gctcttgttg tccaggctgg agtgcaatgg
2401 cacgatctca gctcactgca acctccgcct cccaggttca agtaattctc ctgcctcagc
2461 ctcccgagtg gctgggatta gcggcatgca ccaccacgcc cagctatttt tgtattttta
2521 gtagagatgg ggtttcacca tgttaaccag gatggtctcg atctcttgac ctggtgatct
2581 gcccacctcg gcctgccaaa gtgctgggat tacaggcttg agctaccgcg cccggccgtg
2641 aacgctattt tctaagcagc cagcagtgaa tctaaaactc tggaagaagt cttctgtttg
2701 aaaggcttat ttaagccaca cgtacacaca ctgtcttaga gtactgtgag cccaccccac
2761 attggtcatc ttccctatca cacaaatgat gttattttgg actagcttaa ttttgaaatg
2821 gtaacaaagt ttcctattcc atactgttca tttctaatac tcttacgaaa actattctaa
2881 aggaggcagg agccaaggcc aaaagtgaac gtacaggttt aaaatggctg tgataagggc
2941 cagctggtat taactgataa ctttaccttt gggtttttgt tattttgttt ttctagtccc
3001 tacctgtgtt taaattatgg ataactcgaa agacaggctc aggtgaaggc cgagtaatga
3061 ttttttttga agtttcaatg gtgtgaaata aatttctgtt ctta
安基酸序列:
/translation="MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNF
ISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSS
INDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRN
RFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVL
GSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQ
IKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIV
IMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKG
NEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAV
TDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYA
NISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCP
EVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLL
TVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQF
DEDEKKNRLEKSNPYFMSGANSQKQM"
三篇相關文獻:
1. J Diabetes Complications. 2008 Apr 15;22(3):199-204 [Epub ahead of print]
Influence of Lys656Asn polymorphism of the leptin receptor gene on insulin resistance in nondiabetic obese patients.de Luis DA, Gonzalez Sagrado M, Aller R, Izaola O, Conde R.
Medicine School and Unit of Investigation, Institute of Endocrinology and Nutrition, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain.
2. J Diabetes Complications. 2008 Apr 11 [Epub ahead of print]
Westernized-like-diet-fed rats: effect on glucose homeostasis, lipid profile, and adipocyte hormones and their modulation by rosiglitazone and glimepiride.Schaalan M, El-Abhar HS, Barakat M, El-Denshary ES.
Biochemistry Department, Faculty of Pharmacy, Misr International University (MIU), Cairo, Egypt.
3. Trends Endocrinol Metab. 1998 May-Jun;9(4):146-50.
Central nervous system effects of leptin.Buchanan C, Mahesh V, Zamorano P, Brann D.
Department of Physiology and Endocrinology, Medical College of Georgia, Augusta, GA 30912, USA.
A: Corn(玉米),Cotton(棉花),Oilseeds(油菜子),Watermelon(西瓜),Carrot(胡蘿蔔)
二.ROCHE藥品所治療的疾病包含哪些?
A: Tamitlu - 克流感 - 流行性感冒
Xenical - 羅氏鮮 - 減肥
Herceptin - 賀癌平 - 治癌症
三.PFIZER除威爾剛之外,還有什麼藥?
A: Caverject , Glucotrol , Sinequan
四.Perkin Elmer賣什麼儀器?
A: Lab Automation , Medical Lighting , Raman Spectroscopy
五.ABI需要什麼人才?
A: Sales , Marketing , Purchasing
基因名稱:leptin
基因編碼:NM_005073
基因大小:3104 bp
生物體:Homo sapiens (human)
DNA序列:
1 cacctgccag gagcacgtcc cgccggcagt cgcaggagcc ctgggagccg ccgccatggg
61 aatgtccaaa tcacacagtt tctttggtta tcccctgagc atcttcttca tcgtggtcaa
121 tgagttttgc gaaagatttt cctactatgg aatgcgagca atcctgattc tgtacttcac
181 aaatttcatc agctgggatg ataacctgtc caccgccatc taccatacgt ttgtggctct
241 gtgctacctg acgccaattc tcggagctct tatcgccgac tcgtggctgg gaaagttcaa
301 gaccattgtg tcgctctcca ttgtctacac aattggacaa gcagtcacct cagtaagctc
361 cattaatgac ctcacagacc acaaccatga tggcaccccc gacagccttc ctgtgcacgt
421 ggtgctgtcc ttgatcggcc tggccctgat agctctcggg actggaggaa tcaaaccctg
481 tgtgtctgcg tttggtggag atcagtttga agagggccag gagaaacaaa gaaacagatt
541 tttttccatc ttttacttgg ctattaatgc tggaagtttg ctttccacaa tcatcacacc
601 catgctcaga gttcaacaat gtggaattca cagtaaacaa gcttgttacc cactggcctt
661 tggggttcct gctgctctca tggctgtagc cctgattgtg tttgtccttg gcagtgggat
721 gtacaagaag ttcaagccac agggcaacat catgggtaaa gtggccaagt gcatcggttt
781 tgccatcaaa aatagattta ggcatcggag taaggcattt cccaagaggg agcactggct
841 ggactgggct aaagagaaat acgatgagcg gctcatctcc caaattaaga tggttacgag
901 ggtgatgttc ctgtatattc cactcccaat gttctgggcc ttgtttgacc agcagggctc
961 caggtggaca ctgcaggcaa caactatgtc cgggaaaatc ggagctcttg aaattcagcc
1021 cgatcagatg cagaccgtga acgccatcct gatcgtgatc atggtcccga tcttcgatgc
1081 tgtgctgtac cctctcattg caaaatgtgg cttcaatttc acctccttga agaagatggc
1141 agttggcatg gtcctggcct ccatggcctt tgtggtggct gccatcgtgc aggtggaaat
1201 cgataaaact cttccagtct tccccaaagg aaacgaagtc caaattaaag ttttgaatat
1261 aggaaacaat accatgaata tatctcttcc tggagagatg gtgacacttg gcccaatgtc
1321 tcaaacaaat gcatttatga cttttgatgt aaacaaactg acaaggataa acatttcttc
1381 tcctggatca ccagtcactg ctgtaactga cgacttcaag cagggccaac gccacacgct
1441 tctagtgtgg gcccccaatc actaccaggt ggtaaaggat ggtcttaacc agaagccaga
1501 aaaaggggaa aatggaatca gatttgtaaa tacttttaac gagctcatca ccatcacaat
1561 gagtgggaaa gtttatgcaa acatcagcag ctacaatgcc agcacatacc agttttttcc
1621 ttctggcata aaaggcttca caataagctc aacagagatt ccgccacaat gtcaacctaa
1681 tttcaatact ttctaccttg aatttggtag tgcttatacc tatatagtcc aaaggaagaa
1741 tgacagctgc cctgaagtga aggtgtttga agatatttca gccaacacag ttaacatggc
1801 tctgcaaatc ccgcagtatt ttcttctcac ctgtggcgaa gtggtcttct ctgtcacggg
1861 attggaattc tcatattctc aggctccttc caacatgaag tcggtgcttc aggcaggatg
1921 gctgctgacc gtggctgttg gcaacatcat tgtgctcatc gtggcagggg caggccagtt
1981 cagcaaacag tgggccgagt acattctatt tgccgcgttg cttctggtcg tctgtgtaat
2041 ttttgccatc atggctcggt tctatactta catcaaccca gcggagatcg aagctcaatt
2101 tgatgaggat gaaaagaaaa acagactgga aaagagtaac ccatatttca tgtcaggggc
2161 caattcacag aaacagatgt gaaggtcagg aggcaagtgg aggatggact gggcccgcag
2221 atgccctgac ctctgccccc aggtagcagg acactccatt ggatggcccc tgatgaggaa
2281 gacttcagaa ttgggaacta aaccatgaat gctattttct tttttctttt tcttttcttt
2341 tttttttttt tttttttgag acagagtttt gctcttgttg tccaggctgg agtgcaatgg
2401 cacgatctca gctcactgca acctccgcct cccaggttca agtaattctc ctgcctcagc
2461 ctcccgagtg gctgggatta gcggcatgca ccaccacgcc cagctatttt tgtattttta
2521 gtagagatgg ggtttcacca tgttaaccag gatggtctcg atctcttgac ctggtgatct
2581 gcccacctcg gcctgccaaa gtgctgggat tacaggcttg agctaccgcg cccggccgtg
2641 aacgctattt tctaagcagc cagcagtgaa tctaaaactc tggaagaagt cttctgtttg
2701 aaaggcttat ttaagccaca cgtacacaca ctgtcttaga gtactgtgag cccaccccac
2761 attggtcatc ttccctatca cacaaatgat gttattttgg actagcttaa ttttgaaatg
2821 gtaacaaagt ttcctattcc atactgttca tttctaatac tcttacgaaa actattctaa
2881 aggaggcagg agccaaggcc aaaagtgaac gtacaggttt aaaatggctg tgataagggc
2941 cagctggtat taactgataa ctttaccttt gggtttttgt tattttgttt ttctagtccc
3001 tacctgtgtt taaattatgg ataactcgaa agacaggctc aggtgaaggc cgagtaatga
3061 ttttttttga agtttcaatg gtgtgaaata aatttctgtt ctta
安基酸序列:
/translation="MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNF
ISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSS
INDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRN
RFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVL
GSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQ
IKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIV
IMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKG
NEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAV
TDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYA
NISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCP
EVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLL
TVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQF
DEDEKKNRLEKSNPYFMSGANSQKQM"
三篇相關文獻:
1. J Diabetes Complications. 2008 Apr 15;22(3):199-204 [Epub ahead of print]
Influence of Lys656Asn polymorphism of the leptin receptor gene on insulin resistance in nondiabetic obese patients.de Luis DA, Gonzalez Sagrado M, Aller R, Izaola O, Conde R.
Medicine School and Unit of Investigation, Institute of Endocrinology and Nutrition, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain.
2. J Diabetes Complications. 2008 Apr 11 [Epub ahead of print]
Westernized-like-diet-fed rats: effect on glucose homeostasis, lipid profile, and adipocyte hormones and their modulation by rosiglitazone and glimepiride.Schaalan M, El-Abhar HS, Barakat M, El-Denshary ES.
Biochemistry Department, Faculty of Pharmacy, Misr International University (MIU), Cairo, Egypt.
3. Trends Endocrinol Metab. 1998 May-Jun;9(4):146-50.
Central nervous system effects of leptin.Buchanan C, Mahesh V, Zamorano P, Brann D.
Department of Physiology and Endocrinology, Medical College of Georgia, Augusta, GA 30912, USA.
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